3F4Y
HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence
Summary for 3F4Y
Entry DOI | 10.2210/pdb3f4y/pdb |
Related | 1AIK 3F4Z 3F50 |
Descriptor | Envelope glycoprotein gp160, Mutant peptide derived from HIV gp41 CHR domain (3 entities in total) |
Functional Keywords | helix bundle, aids, apoptosis, cell membrane, cleavage on pair of basic residues, coiled coil, envelope protein, fusion protein, glycoprotein, host-virus interaction, lipoprotein, membrane, palmitate, transmembrane, viral immunoevasion, virion, viral protein |
Cellular location | Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04580 |
Total number of polymer chains | 6 |
Total formula weight | 25787.30 |
Authors | Horne, W.S.,Gellman, S.H. (deposition date: 2008-11-03, release date: 2009-09-15, Last modification date: 2023-12-27) |
Primary citation | Horne, W.S.,Johnson, L.M.,Ketas, T.J.,Klasse, P.J.,Lu, M.,Moore, J.P.,Gellman, S.H. Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers Proc.Natl.Acad.Sci.USA, 106:14751-14756, 2009 Cited by PubMed: 19706443DOI: 10.1073/pnas.0902663106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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