3EPG
Structure of Human DNA Polymerase Iota complexed with N2-ethylguanine
Summary for 3EPG
Entry DOI | 10.2210/pdb3epg/pdb |
Related | 2ALZ 2FLP 3epi |
Descriptor | DNA polymerase iota, 5'-D(*DTP*DCP*DTP*(2EG)P*DGP*DGP*DGP*DTP*DCP*DCP*DTP*DAP*DGP*DGP*DAP*DCP*DCP*(DOC))-3', 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | dna pol iota, lesion bypass, n2-ethylguanine, dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, magnesium, metal-binding, mutator protein, nucleotidyltransferase, nucleus, schiff base, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q9UNA4 |
Total number of polymer chains | 3 |
Total formula weight | 58627.67 |
Authors | Pence, M.G. (deposition date: 2008-09-29, release date: 2008-12-16, Last modification date: 2023-09-06) |
Primary citation | Pence, M.G.,Blans, P.,Zink, C.N.,Hollis, T.,Fishbein, J.C.,Perrino, F.W. Lesion bypass of N2-ethylguanine by human DNA polymerase iota. J.Biol.Chem., 284:1732-1740, 2009 Cited by PubMed: 18984581DOI: 10.1074/jbc.M807296200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report