3EIQ

Crystal structure of Pdcd4-eIF4A

Summary for 3EIQ

• Entry DOI: 10.2210/pdb3eiq/pdb
• Descriptor: Eukaryotic initiation factor 4A-I, Programmed cell death protein 4 (2 entities in total)
• Functional Keywords: pdcd4, anti-oncogene, apoptosis, cell cycle, nucleus, phosphoprotein, rna-binding, atp-binding, helicase, hydrolase, initiation factor, nucleotide-binding, protein biosynthesis, antitumor protein, translation, hydrolase-antitumor protein complex, hydrolase/antitumor protein
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P60842
• Total number of polymer chains: 3
• Total formula weight: 133827.52

Authors

Loh, P.G.,Cheng, Z.,Song, H. (deposition date: 2008-09-17, release date: 2009-02-24, Last modification date: 2023-11-01)

• Primary citation: Loh, P.G.,Yang, H.S.,Walsh, M.A.,Wang, Q.,Wang, X.,Cheng, Z.,Liu, D.,Song, H.; Structural basis for translational inhibition by the tumour suppressor Pdcd4; Embo J., 28:274-285, 2009; PubMed: 19153607; DOI: 10.1038/emboj.2008.278

Experimental method

X-RAY DIFFRACTION (3.5 Å)