3EG5
Crystal structure of MDIA1-TSH GBD-FH3 in complex with CDC42-GMPPNP
Summary for 3EG5
Entry DOI | 10.2210/pdb3eg5/pdb |
Related | 1Z2C 2BAP |
Descriptor | Cell division control protein 42 homolog, Protein diaphanous homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total) |
Functional Keywords | protein-protein complex, rho proteins, diaphanous, formins, armadillo repeat, g-protein, gtpase, alternative splicing, cell membrane, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, prenylation, actin-binding, cell projection, coiled coil, cytoplasm, cytoskeleton, phosphoprotein, ubl conjugation, signaling protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P60766 Cell membrane: O08808 |
Total number of polymer chains | 4 |
Total formula weight | 129099.80 |
Authors | Lammers, M.,Meyer, S.,Kuehlmann, D.,Wittinghofer, A. (deposition date: 2008-09-10, release date: 2008-10-14, Last modification date: 2023-11-01) |
Primary citation | Lammers, M.,Meyer, S.,Kuhlmann, D.,Wittinghofer, A. Specificity of Interactions between mDia Isoforms and Rho Proteins J.Biol.Chem., 283:35236-35246, 2008 Cited by PubMed: 18829452DOI: 10.1074/jbc.M805634200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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