3EFI

Carbonic anhydrase activators: Kinetic and X-ray crystallographic study for the interaction of d- and l-tryptophan with the mammalian isoforms I-XIV

Summary for 3EFI

Entry DOI	10.2210/pdb3efi/pdb
Descriptor	Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ... (5 entities in total)
Functional Keywords	carbonic anhydrase, activators, aminoacids, oxo-acid, acetylation, cytoplasm, disease mutation, lyase, metal-binding, polymorphism, zinc
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29880.40
Authors	Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T. (deposition date: 2008-09-09, release date: 2008-09-30, Last modification date: 2023-11-01)
Primary citation	Temperini, C.,Innocenti, A.,Scozzafava, A.,Supuran, C.T. Carbonic anhydrase activators: kinetic and X-ray crystallographic study for the interaction of D- and L-tryptophan with the mammalian isoforms I-XIV Bioorg.Med.Chem., 16:8373-8378, 2008 Cited by PubMed: 18774300 DOI: 10.1016/j.bmc.2008.08.043 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation