3EA5
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Summary for 3EA5
Entry DOI | 10.2210/pdb3ea5/pdb |
Descriptor | GTP-binding nuclear protein Ran, Importin subunit beta-1, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | karyopherin, importin, ran, gtp-binding, host-virus interaction, nucleotide-binding, nucleus, phosphoprotein, protein transport, transport, transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P62826 Cytoplasm (By similarity): Q06142 |
Total number of polymer chains | 4 |
Total formula weight | 239678.54 |
Authors | Forwood, J.K.,Lonhienne, J.K.,Guncar, G.,Stewart, M.,Marfori, M.,Kobe, B. (deposition date: 2008-08-24, release date: 2008-10-21, Last modification date: 2024-02-21) |
Primary citation | Forwood, J.K.,Lonhienne, T.G.,Marfori, M.,Robin, G.,Meng, W.,Guncar, G.,Liu, S.M.,Stewart, M.,Carroll, B.J.,Kobe, B. Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics. J.Mol.Biol., 383:772-782, 2008 Cited by PubMed: 18708071DOI: 10.1016/j.jmb.2008.07.090 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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