3E9L
Crystal Structure of Human Prp8, Residues 1755-2016
Summary for 3E9L
Entry DOI | 10.2210/pdb3e9l/pdb |
Related | 3E9O 3E9P |
Descriptor | Pre-mRNA-processing-splicing factor 8, SODIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | nucleotidyl transfer, disease mutation, mrna processing, mrna splicing, nucleus, phosphoprotein, retinitis pigmentosa, rna-binding, sensory transduction, spliceosome, vision, rna binding protein, splicing |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus speckle (By similarity): Q6P2Q9 |
Total number of polymer chains | 1 |
Total formula weight | 29593.67 |
Authors | Pena, V.,Rozov, A.,Wahl, M.C. (deposition date: 2008-08-22, release date: 2008-10-07, Last modification date: 2024-02-21) |
Primary citation | Pena, V.,Rozov, A.,Fabrizio, P.,Luhrmann, R.,Wahl, M.C. Structure and function of an RNase H domain at the heart of the spliceosome. Embo J., 27:2929-2940, 2008 Cited by PubMed: 18843295DOI: 10.1038/emboj.2008.209 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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