3DYL
human phosphdiesterase 9 substrate complex (ES complex)
Summary for 3DYL
Entry DOI | 10.2210/pdb3dyl/pdb |
Related | 3DY8 3DYN 3DYQ 3DYS |
Descriptor | human phosphodiesterase 9, MANGANESE (II) ION, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | phosphodiesterase, enzyme mechanism, cgmp, hydrolase, manganese, metal-binding, phosphoprotein |
Biological source | Homo sapiens (Human) |
Cellular location | Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083 |
Total number of polymer chains | 2 |
Total formula weight | 78497.81 |
Authors | Liu, S.,Mansour, M.N.,Dillman, K.,Perez, J.,Danley, D.,Menniti, F. (deposition date: 2008-07-28, release date: 2008-09-16, Last modification date: 2024-02-21) |
Primary citation | Liu, S.,Mansour, M.N.,Dillman, K.S.,Perez, J.R.,Danley, D.E.,Aeed, P.A.,Simons, S.P.,Lemotte, P.K.,Menniti, F.S. Structural basis for the catalytic mechanism of human phosphodiesterase 9. Proc.Natl.Acad.Sci.Usa, 105:13309-13314, 2008 Cited by PubMed: 18757755DOI: 10.1073/pnas.0708850105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report