3DW8
Structure of a Protein Phosphatase 2A Holoenzyme with B55 subunit
Summary for 3DW8
Entry DOI | 10.2210/pdb3dw8/pdb |
Related PRD ID | PRD_000212 |
Descriptor | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (5 entities in total) |
Functional Keywords | holoenzyme, b55, pr55, wd repeat, hydrolase, iron, manganese, metal-binding, methylation, phosphoprotein, protein phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens More |
Cellular location | Cytoplasm (By similarity): P30153 Cytoplasm: P67775 |
Total number of polymer chains | 8 |
Total formula weight | 306541.98 |
Authors | Xu, Y.,Chen, Y.,Zhang, P.,Jeffrey, P.D.,Shi, Y. (deposition date: 2008-07-21, release date: 2008-10-07, Last modification date: 2024-04-03) |
Primary citation | Xu, Y.,Chen, Y.,Zhang, P.,Jeffrey, P.D.,Shi, Y. Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation. Mol.Cell, 31:873-885, 2008 Cited by PubMed: 18922469DOI: 10.1016/j.molcel.2008.08.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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