3DF0
Calcium-dependent complex between m-calpain and calpastatin
Summary for 3DF0
Entry DOI | 10.2210/pdb3df0/pdb |
Descriptor | Calpain-2 catalytic subunit, Calpain small subunit 1, Calpastatin, ... (4 entities in total) |
Functional Keywords | protease core domain, penta ef-hand domains, c2-like domain, inhibitor loop-out, hydrolase, membrane, protease, thiol protease, phosphoprotein, protease inhibitor, thiol protease inhibitor |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm : Q07009 Q64537 |
Total number of polymer chains | 3 |
Total formula weight | 112562.88 |
Authors | Moldoveanu, T.,Gehring, K.,Green, D.R. (deposition date: 2008-06-11, release date: 2008-11-11, Last modification date: 2023-08-30) |
Primary citation | Moldoveanu, T.,Gehring, K.,Green, D.R. Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature, 456:404-408, 2008 Cited by PubMed: 19020622DOI: 10.1038/nature07353 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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