3D7C

Crystal structure of the bromodomain of human GCN5, the general control of amino-acid synthesis protein 5-like 2

Summary for 3D7C

Entry DOI	10.2210/pdb3d7c/pdb
Descriptor	General control of amino acid synthesis protein 5-like 2 (2 entities in total)
Functional Keywords	gcn5, bromodomain, amino-acid synthesis, structural genomics consortium, sgc, host-virus interaction, nucleus, phosphoprotein, transcription, transcription regulation, transferase, biosynthetic protein
Biological source	Homo sapiens
Cellular location	Nucleus: Q92830
Total number of polymer chains	2
Total formula weight	26574.63
Authors	Filippakopoulos, P.,Eswaran, J.,Picaud, S.,Fedorov, O.,Murray, J.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2008-05-21, release date: 2008-07-15, Last modification date: 2023-08-30)
Primary citation	Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331 DOI: 10.1016/j.cell.2012.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation