3D48
Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor
Summary for 3D48
Entry DOI | 10.2210/pdb3d48/pdb |
Related | 1BP3 1F6F 1N9D 1RW5 2Q98 |
Descriptor | Prolactin, Prolactin receptor, CARBONATE ION, ... (4 entities in total) |
Functional Keywords | cytokine-cytokine receptor complex, four-helix bundle, glycoprotein, hormone, lactation, secreted, alternative splicing, membrane, receptor, transmembrane, hormone-hormone receptor complex, hormone/hormone receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01236 Membrane ; Single-pass type I membrane protein . Isoform 7: Secreted: P16471 |
Total number of polymer chains | 2 |
Total formula weight | 46717.89 |
Authors | Svensson, L.A.,Breinholt, J. (deposition date: 2008-05-14, release date: 2008-06-03, Last modification date: 2023-11-01) |
Primary citation | Svensson, L.A.,Bondensgaard, K.,Norskov-Lauritsen, L.,Christensen, L.,Becker, P.,Andersen, M.D.,Maltesen, M.J.,Rand, K.D.,Breinholt, J. Crystal structure of a prolactin receptor antagonist bound to the extracellular domain of the prolactin receptor J.Biol.Chem., 283:19085-19094, 2008 Cited by PubMed: 18467331DOI: 10.1074/jbc.M801202200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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