3D2V

Structure of the eukaryotic TPP-specific riboswitch bound to the antibacterial compound pyrithiamine pyrophosphate

Summary for 3D2V

• Entry DOI: 10.2210/pdb3d2v/pdb
• Related: 2cky 3d2g 3D2X
• Descriptor: TPP-specific riboswitch, MAGNESIUM ION, 1-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-2-METHYLPYRIDINIUM, ... (4 entities in total)
• Functional Keywords: rna, riboswitch, antibiotic, thiamine pyrophosphate, pyrithiamine pyrophosphate, complex
• Biological source: Arabidopsis thaliana
• Total number of polymer chains: 2
• Total formula weight: 50999.30

Authors

Thore, S.,Frick, C.,Ban, N. (deposition date: 2008-05-09, release date: 2008-07-01, Last modification date: 2023-08-30)

• Primary citation: Thore, S.,Frick, C.,Ban, N.; Structural basis of thiamine pyrophosphate analogues binding to the eukaryotic riboswitch; J.Am.Chem.Soc., 130:8116-8117, 2008; PubMed: 18533652; DOI: 10.1021/ja801708e

Experimental method

X-RAY DIFFRACTION (2 Å)