3D24
Crystal structure of ligand-binding domain of estrogen-related receptor alpha (ERRalpha) in complex with the peroxisome proliferators-activated receptor coactivator-1alpha box3 peptide (PGC-1alpha)
Summary for 3D24
Entry DOI | 10.2210/pdb3d24/pdb |
Related | 1XB7 |
Descriptor | Steroid hormone receptor ERR1, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (3 entities in total) |
Functional Keywords | nuclear receptor, ligand binding domain, coactivator, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, zinc, zinc-finger, polymorphism, rna-binding, structural genomics, structural proteomics in europe, spine |
Biological source | Homo sapiens More |
Cellular location | Nucleus: P11474 Q9UBK2 |
Total number of polymer chains | 4 |
Total formula weight | 60501.74 |
Authors | Moras, D.,Greschik, H.,Flaig, R.,Sato, Y.,Rochel, N.,Structural Proteomics in Europe (SPINE) (deposition date: 2008-05-07, release date: 2008-06-10, Last modification date: 2023-08-30) |
Primary citation | Greschik, H.,Althage, M.,Flaig, R.,Sato, Y.,Chavant, V.,Peluso-Iltis, C.,Choulier, L.,Cronet, P.,Rochel, N.,Schule, R.,Stromstedt, P.E.,Moras, D. Communication between the ERR{alpha} Homodimer Interface and the PGC-1{alpha} Binding Surface via the Helix 8-9 Loop. J.Biol.Chem., 283:20220-20230, 2008 Cited by PubMed: 18441008DOI: 10.1074/jbc.M801920200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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