1XB7

X-ray structure of ERRalpha LBD in complex with a PGC-1alpha peptide at 2.5A resolution

Summary for 1XB7

Entry DOI	10.2210/pdb1xb7/pdb
Descriptor	Steroid hormone receptor ERR1, Peroxisome proliferator activated receptor gamma coactivator 1 alpha, IODIDE ION, ... (4 entities in total)
Functional Keywords	nuclear hormone receptor, ligand binding domain, three-layered alpha-helical sandwich, coactivator peptide, amphipathic alpha-helix, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P11474 Q9UBK2
Total number of polymer chains	2
Total formula weight	28553.69
Authors	Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Filipuzzi, I.,Schilb, A.,Riou, V.,Graham, A.,Strauss, A.,Geiser, M.,Fournier, B. (deposition date: 2004-08-30, release date: 2004-09-14, Last modification date: 2023-10-25)
Primary citation	Kallen, J.,Schlaeppi, J.M.,Bitsch, F.,Filipuzzi, I.,Schilb, A.,Riou, V.,Graham, A.,Strauss, A.,Geiser, M.,Fournier, B. Evidence for Ligand-independent Transcriptional Activation of the Human Estrogen-related Receptor {alpha} (ERR{alpha}): CRYSTAL STRUCTURE OF ERR{alpha} LIGAND BINDING DOMAIN IN COMPLEX WITH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR COACTIVATOR-1{alpha} J.Biol.Chem., 279:49330-49337, 2004 Cited by PubMed: 15337744 DOI: 10.1074/jbc.M407999200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation