3CU7
Human Complement Component 5
Summary for 3CU7
Entry DOI | 10.2210/pdb3cu7/pdb |
Descriptor | Complement C5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | mg domain, complement, inflammation, anaphylatoxin, cleavage on pair of basic residues, complement alternate pathway, complement pathway, cytolysis, glycoprotein, immune response, inflammatory response, innate immunity, membrane attack complex, secreted, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 379355.17 |
Authors | Fredslund, F.,Andersen, G.R. (deposition date: 2008-04-16, release date: 2008-06-10, Last modification date: 2023-11-01) |
Primary citation | Fredslund, F.,Laursen, N.S.,Roversi, P.,Jenner, L.,Oliveira, C.L.P.,Pedersen, J.S.,Nunn, M.A.,Lea, S.M.,Discipio, R.,Sottrup-Jensen, L.,Andersen, G.R. Structure of and influence of a tick complement inhibitor on human complement component 5 Nat.Immunol., 9:753-760, 2008 Cited by PubMed: 18536718DOI: 10.1038/ni.1625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.105 Å) |
Structure validation
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