3CLH
Crystal structure of 3-dehydroquinate synthase (DHQS)from Helicobacter pylori
Summary for 3CLH
Entry DOI | 10.2210/pdb3clh/pdb |
Descriptor | 3-dehydroquinate synthase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | shikimate pathway, aromatic amino acid biosynthesis, dhqs, amino-acid biosynthesis, cytoplasm, lyase, nad |
Biological source | Helicobacter pylori (Campylobacter pylori) |
Cellular location | Cytoplasm (Probable): P56081 |
Total number of polymer chains | 2 |
Total formula weight | 79809.30 |
Authors | Wang, W.C.,Liu, J.S.,Cheng, W.C.,Wang, H.J.,Chen, Y.C. (deposition date: 2008-03-19, release date: 2009-03-24, Last modification date: 2023-11-01) |
Primary citation | Liu, J.S.,Cheng, W.C.,Wang, H.J.,Chen, Y.C.,Wang, W.C. Structure-based inhibitor discovery of Helicobacter pylori dehydroquinate synthase. Biochem.Biophys.Res.Commun., 373:1-7, 2008 Cited by PubMed: 18503755DOI: 10.1016/j.bbrc.2008.05.070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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