3CKH
Crystal structure of Eph A4 receptor
Summary for 3CKH
Entry DOI | 10.2210/pdb3ckh/pdb |
Related | 1NUK 2BBA |
Descriptor | Ephrin type-A receptor 4 (2 entities in total) |
Functional Keywords | eph receptor, atp-binding, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, transferase, transmembrane, tyrosine-protein kinase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type I membrane protein: P54764 |
Total number of polymer chains | 2 |
Total formula weight | 41691.25 |
Authors | Shi, J.H.,Song, J.X. (deposition date: 2008-03-15, release date: 2008-09-23, Last modification date: 2023-11-01) |
Primary citation | Qin, H.,Shi, J.,Noberini, R.,Pasquale, E.B.,Song, J. Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor. J.Biol.Chem., 283:29473-29484, 2008 Cited by PubMed: 18708347DOI: 10.1074/jbc.M804114200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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