3CE4
Structure of Macrophage Migration Inhibitory Factor Covalently Inhibited by PMSF Treatment
Summary for 3CE4
Entry DOI | 10.2210/pdb3ce4/pdb |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, phenylmethanesulfonic acid, ... (6 entities in total) |
Functional Keywords | covalent modification, covalent inhibition, cytokine, inflammatory response, isomerase, phosphoprotein |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P14174 |
Total number of polymer chains | 3 |
Total formula weight | 38458.56 |
Authors | Crichlow, G.V.,Lolis, E. (deposition date: 2008-02-28, release date: 2008-12-30, Last modification date: 2023-08-30) |
Primary citation | Crichlow, G.V.,Lubetsky, J.B.,Leng, L.,Bucala, R.,Lolis, E.J. Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions. Biochemistry, 48:132-139, 2009 Cited by PubMed: 19090677DOI: 10.1021/bi8014423 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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