3C9E

Crystal structure of the cathepsin K : chondroitin sulfate complex.

Summary for 3C9E

Entry DOI	10.2210/pdb3c9e/pdb
Descriptor	Cathepsin K, 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, CALCIUM ION, ... (5 entities in total)
Functional Keywords	n:1 cathepsin k : chondroitin sulfate complex, "beads-on-a-string" organization, hydrolase, lysosome, protease, thiol protease
Biological source	Homo sapiens (Human)
Cellular location	Lysosome: P43235
Total number of polymer chains	1
Total formula weight	25320.14
Authors	Kienetz, M.,Cherney, M.M.,James, M.N.G.,Bromme, D. (deposition date: 2008-02-15, release date: 2008-08-26, Last modification date: 2020-07-29)
Primary citation	Li, Z.,Kienetz, M.,Cherney, M.M.,James, M.N.,Bromme, D. The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex. J.Mol.Biol., 383:78-91, 2008 Cited by PubMed: 18692071 DOI: 10.1016/j.jmb.2008.07.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation