3C84

Crystal structure of a complex of AChBP from aplysia californica and the neonicotinoid thiacloprid

Summary for 3C84

Entry DOI	10.2210/pdb3c84/pdb
Related	3C79
Descriptor	Soluble acetylcholine receptor, {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide, ISOPROPYL ALCOHOL, ... (5 entities in total)
Functional Keywords	acetylcholine binding protein, neonicotinoid, receptor, choline-binding protein
Biological source	Aplysia californica (California sea hare)
Total number of polymer chains	5
Total formula weight	130743.89
Authors	Talley, T.T.,Harel, M.,Hibbs, R.E.,Tomizawa, M.,Casida, J.E.,Taylor, P.W. (deposition date: 2008-02-08, release date: 2008-05-20, Last modification date: 2023-08-30)
Primary citation	Talley, T.T.,Harel, M.,Hibbs, R.E.,Radic, Z.,Tomizawa, M.,Casida, J.E.,Taylor, P. Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proc.Natl.Acad.Sci.Usa, 105:7606-7611, 2008 Cited by PubMed: 18477694 DOI: 10.1073/pnas.0802197105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation