3C4B
Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer
Summary for 3C4B
Entry DOI | 10.2210/pdb3c4b/pdb |
Related | 3C4T |
Descriptor | Endoribonuclease Dicer (2 entities in total) |
Functional Keywords | rnase, dsrna binding protein, atp-binding, endonuclease, helicase, hydrolase, nuclease, nucleotide-binding, phosphoprotein, rna-binding, rna-mediated gene silencing |
Biological source | Mus musculus (house mouse) |
Cellular location | Cytoplasm (By similarity): Q8R418 |
Total number of polymer chains | 1 |
Total formula weight | 30971.91 |
Authors | Lee, J.K.,Du, Z.,Tjhen, R.J.,Stroud, R.M.,James, T.L. (deposition date: 2008-01-29, release date: 2008-02-19, Last modification date: 2011-07-13) |
Primary citation | Du, Z.,Lee, J.K.,Tjhen, R.,Stroud, R.M.,James, T.L. Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage. Proc.Natl.Acad.Sci.Usa, 105:2391-2396, 2008 Cited by PubMed: 18268334DOI: 10.1073/pnas.0711506105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.68 Å) |
Structure validation
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