3BVN
High resolution crystal structure of HLA-B*1402 in complex with the latent membrane protein 2 peptide (LMP2) of Epstein-Barr virus
Summary for 3BVN
Entry DOI | 10.2210/pdb3bvn/pdb |
Related | 1UXS |
Descriptor | HLA class I histocompatibility antigen, B*1402 alpha chain, Beta-2-microglobulin, Latent membrane protein 2 peptide, ... (4 entities in total) |
Functional Keywords | major histocompatibility complex, mhc, human leukocyte antigen, hla, hla-b14, hla-b*14, hla-b1402, hla-b*1402, plmp2, ankylosing spondylitis, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, alternative splicing, cytoplasm, host-virus interaction, membrane, phosphoprotein, transmembrane, ubl conjugation, immune system |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P61769 Isoform LMP2A: Host cell membrane; Multi- pass membrane protein. Isoform LMP2B: Host endomembrane system; Multi-pass membrane protein: P13285 |
Total number of polymer chains | 6 |
Total formula weight | 90710.59 |
Authors | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (deposition date: 2008-01-07, release date: 2009-02-03, Last modification date: 2023-08-30) |
Primary citation | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A. Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284:29784-29797, 2009 Cited by PubMed: 19617632DOI: 10.1074/jbc.M109.038497 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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