3BL2

Crystal Structure of M11, the BCL-2 Homolog of Murine Gamma-herpesvirus 68, Complexed with Mouse Beclin1 (residues 106-124)

Summary for 3BL2

Entry DOI	10.2210/pdb3bl2/pdb
Descriptor	V-bcl-2, Beclin-1 (3 entities in total)
Functional Keywords	protein-protein complex, viral bcl-2, beclin1, apoptosis, m11, autophagy, antiviral defense, coiled coil, cytoplasm, golgi apparatus, membrane, viral protein-apoptosis complex, viral protein/apoptosis
Biological source	Murid herpesvirus 4 (Murine herpesvirus 68) More
Cellular location	Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : O88597
Total number of polymer chains	4
Total formula weight	34789.75
Authors	Oh, B.-H.,Woo, J.-S.,Ku, B. (deposition date: 2007-12-10, release date: 2008-02-12, Last modification date: 2023-11-01)
Primary citation	Ku, B.,Woo, J.-S.,Liang, C.,Lee, K.-H.,Hong, H.-S.,E, X.,Kim, K.-S.,Jung, J.U.,Oh, B.-H. Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine gamma-Herpesvirus 68 Plos Pathog., 4:e25-e25, 2008 Cited by PubMed: 18248095 DOI: 10.1371/journal.ppat.0040025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation