3BK3
Crystal structure of the complex of BMP-2 and the first Von Willebrand domain type C of Crossveinless-2
Summary for 3BK3
Entry DOI | 10.2210/pdb3bk3/pdb |
Related | 1REW 2H62 2H64 |
Descriptor | Bone morphogenetic protein 2, Crossveinless 2 (3 entities in total) |
Functional Keywords | tgf-beta superfamily, bmp modulator proteins, chordin, bmp inhibitor, chondrogenesis, cleavage on pair of basic residues, cytokine, developmental protein, differentiation, glycoprotein, growth factor, osteogenesis, polymorphism, secreted, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P12643 |
Total number of polymer chains | 4 |
Total formula weight | 40136.38 |
Authors | Mueller, T.D.,Sebald, W.,Zhang, J.-L. (deposition date: 2007-12-05, release date: 2008-05-27, Last modification date: 2021-11-10) |
Primary citation | Zhang, J.-L.,Qiu, L.-Y.,Kotzsch, A.,Weidauer, S.,Patterson, L.,Hammerschmidt, M.,Sebald, W.,Mueller, T.D. Crystal structure analysis reveals how the Chordin family member crossveinless 2 blocks BMP-2 receptor binding Dev.Cell, 14:739-750, 2008 Cited by PubMed: 18477456DOI: 10.1016/j.devcel.2008.02.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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