3BG9
Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus) F1077A Mutant
Summary for 3BG9
Entry DOI | 10.2210/pdb3bg9/pdb |
Related | 1rqh 3BG3 3BG5 |
Descriptor | Pyruvate carboxylase, mitochondrial, MANGANESE (II) ION (2 entities in total) |
Functional Keywords | tim barrel, atp-binding, biotin, disease mutation, gluconeogenesis, ligase, lipid synthesis, manganese, mitochondrion, multifunctional enzyme, nucleotide-binding, phosphoprotein, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P11498 |
Total number of polymer chains | 4 |
Total formula weight | 315100.63 |
Authors | |
Primary citation | Xiang, S.,Tong, L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15:295-302, 2008 Cited by PubMed: 18297087DOI: 10.1038/nsmb.1393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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