3B98

Crystal structure of zebrafish prostacyclin synthase (cytochrome P450 8A1)

Summary for 3B98

Entry DOI	10.2210/pdb3b98/pdb
Related	3B6H 3B99
Descriptor	Prostaglandin I2 synthase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	prostacyclin synthase, cytochrome p450 8a1, cyp8a1, isomerase
Biological source	Danio rerio (zebrafish)
Total number of polymer chains	2
Total formula weight	110930.83
Authors	Li, Y.-C.,Chiang, C.-W.,Yeh, H.-C.,Hsu, P.-Y.,Whitby, F.G.,Wang, L.-H.,Chan, N.-L. (deposition date: 2007-11-03, release date: 2007-11-20, Last modification date: 2023-11-01)
Primary citation	Li, Y.-C.,Chiang, C.-W.,Yeh, H.-C.,Hsu, P.-Y.,Whitby, F.G.,Wang, L.-H.,Chan, N.-L. Structures of Prostacyclin Synthase and Its Complexes with Substrate Analog and Inhibitor Reveal a Ligand-specific Heme Conformation Change J.Biol.Chem., 283:2917-2926, 2008 Cited by PubMed: 18032380 DOI: 10.1074/jbc.M707470200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.08 Å)

Structure validation