3B7U
Leukotriene A4 Hydrolase Complexed with KELatorphan
Summary for 3B7U
Entry DOI | 10.2210/pdb3b7u/pdb |
Related | 2R59 3B7R 3B7S 3B7T |
Descriptor | Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... (7 entities in total) |
Functional Keywords | transition state, analogue peptide, hydrolysis, alternative splicing, cytoplasm, hydrolase, leukotriene biosynthesis, metal-binding, metalloprotease, multifunctional enzyme, protease, zinc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 71069.62 |
Authors | Tholander, F.,Haeggstrom, J.,Thunnissen, M.,Muroya, A.,Roques, B.-P.,Fournie-Zaluski, M.-C. (deposition date: 2007-10-31, release date: 2008-09-16, Last modification date: 2023-08-30) |
Primary citation | Tholander, F.,Muroya, A.,Roques, B.P.,Fournie-Zaluski, M.C.,Thunnissen, M.M.,Haeggstrom, J.Z. Structure-based dissection of the active site chemistry of leukotriene a4 hydrolase: implications for m1 aminopeptidases and inhibitor design. Chem.Biol., 15:920-929, 2008 Cited by PubMed: 18804029DOI: 10.1016/j.chembiol.2008.07.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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