3NYN

Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin

Summary for 3NYN

Entry DOI	10.2210/pdb3nyn/pdb
Related	2ACX 3NYO
Descriptor	G protein-coupled receptor kinase 6, SANGIVAMYCIN, SULFATE ION, ... (5 entities in total)
Functional Keywords	kinase, grk, rgs homology domain, g protein-coupled receptor kinase, transferase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Lipid-anchor: P43250
Total number of polymer chains	2
Total formula weight	134107.24
Authors	Tesmer, J.J.G.,Singh, P. (deposition date: 2010-07-15, release date: 2010-09-22, Last modification date: 2024-02-21)
Primary citation	Boguth, C.A.,Singh, P.,Huang, C.C.,Tesmer, J.J. Molecular basis for activation of G protein-coupled receptor kinases. Embo J., 29:3249-3259, 2010 Cited by PubMed: 20729810 DOI: 10.1038/emboj.2010.206 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.72 Å)

Structure validation