2ZPP

Neutron crystal structure of cubic insulin at pD9

Summary for 2ZPP

Entry DOI	10.2210/pdb2zpp/pdb
Related	2EFA
Descriptor	Insulin A chain, Insulin B chain (3 entities in total)
Functional Keywords	hormone, cubic, porcine insulin, carbohydrate metabolism, cleavage on pair of basic residues, glucose metabolism, secreted
Biological source	Sus scrofa (Pig) More
Cellular location	Secreted: P01315 P01315
Total number of polymer chains	2
Total formula weight	5787.63
Authors	Ishikawa, T.,Tanaka, I.,Niimura, N. (deposition date: 2008-07-26, release date: 2008-10-28, Last modification date: 2023-11-01)
Primary citation	Ishikawa, T.,Chatake, T.,Morimoto, Y.,Maeda, M.,Kurihara, K.,Tanaka, I.,Niimura, N. An abnormal pK(a) value of internal histidine of the insulin molecule revealed by neutron crystallographic analysis Biochem.Biophys.Res.Commun., 376:32-35, 2008 Cited by PubMed: 18725203 DOI: 10.1016/j.bbrc.2008.08.071 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2.5 Å)

Structure validation