2ZNE
Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide
Summary for 2ZNE
Entry DOI | 10.2210/pdb2zne/pdb |
Related | 2ZN8 2ZN9 2ZND |
Descriptor | Programmed cell death protein 6, 16-meric peptide from Programmed cell death 6-interacting protein, ZINC ION, ... (5 entities in total) |
Functional Keywords | penta-ef-hand protein, calcium binding protein, apoptosis, endoplasmic reticulum, membrane, nucleus, polymorphism, cytoplasm, host-virus interaction, protein transport, transport |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus membrane; Peripheral membrane protein: O75340 Cytoplasm, cytosol: Q8WUM4 |
Total number of polymer chains | 4 |
Total formula weight | 43867.30 |
Authors | Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. (deposition date: 2008-04-22, release date: 2008-09-09, Last modification date: 2023-11-01) |
Primary citation | Suzuki, H.,Kawasaki, M.,Inuzuka, T.,Okumura, M.,Kakiuchi, T.,Shibata, H.,Wakatsuki, S.,Maki, M. Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism Structure, 16:1562-1573, 2008 Cited by PubMed: 18940611DOI: 10.1016/j.str.2008.07.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report