2ZJF

Crystal structure of Mycobacterium tuberculosis epoxide hydrolase B complexed with an inhibitor

Summary for 2ZJF

• Entry DOI: 10.2210/pdb2zjf/pdb
• Related: 2E3J
• Descriptor: Probable epoxide hydrolase ephB, ACETATE ION, 1,3-DIPHENYLUREA, ... (4 entities in total)
• Functional Keywords: hydrolase fold, inhibitor, enzyme mechanism, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, hydrolase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 40523.38

Authors

Biswal, B.K.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2008-03-07, release date: 2008-04-01, Last modification date: 2023-08-30)

• Primary citation: Biswal, B.K.,Morisseau, C.,Garen, G.,Cherney, M.M.,Garen, C.,Niu, C.,Hammock, B.D.,James, M.N.; The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor.; J.Mol.Biol., 381:897-912, 2008; PubMed: 18585390; DOI: 10.1016/j.jmb.2008.06.030

Experimental method

X-RAY DIFFRACTION (2.4 Å)