2ZCK

Crystal structure of a ternary complex between PSA, a substrat-acyl intermediate and an activating antibody

Summary for 2ZCK

Entry DOI	10.2210/pdb2zck/pdb
Related	2ZCH 2ZCL
Descriptor	Prostate-specific antigen, KGISSQY, monoclonal antibody 8G8F5 Fab, ... (6 entities in total)
Functional Keywords	human psa, antibodies, kallikrein related peptidases, prostate cancer, glycoprotein, hydrolase, protease, secreted, serine protease, zymogen, immune system
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P07288
Total number of polymer chains	4
Total formula weight	75558.69
Authors	Menez, R.,Stura, E.,Jolivet-Reynaud, C. (deposition date: 2007-11-09, release date: 2008-01-29, Last modification date: 2023-11-01)
Primary citation	Michel, S.,Muller, B.H.,Bossus, M.,Ducancel, F.,Jolivet-Reynaud, C.,Stura, E.A. Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody J.Mol.Biol., 376:1021-1033, 2008 Cited by PubMed: 18187150 DOI: 10.1016/j.jmb.2007.11.052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation