2ZAS
Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with 4-alpha-cumylphenol, a bisphenol A derivative
Summary for 2ZAS
Entry DOI | 10.2210/pdb2zas/pdb |
Related | 2E2R |
Descriptor | Estrogen-related receptor gamma, 4-(1-methyl-1-phenylethyl)phenol, GLYCEROL, ... (4 entities in total) |
Functional Keywords | err gamma, bpa, 4-alpha-cumylphenol, nuclear receptor, transcription, activator, dna-binding, metal-binding, nucleus, transcription regulation, zinc-finger |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P62508 |
Total number of polymer chains | 1 |
Total formula weight | 27915.52 |
Authors | Matsushima, A.,Kakuta, Y.,Teramoto, T.,Shimohigashi, Y. (deposition date: 2007-10-09, release date: 2008-10-07, Last modification date: 2023-11-01) |
Primary citation | Matsushima, A.,Teramoto, T.,Okada, H.,Liu, X.,Tokunaga, T.,Kakuta, Y.,Shimohigashi, Y. ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner Biochem.Biophys.Res.Commun., 373:408-413, 2008 Cited by PubMed: 18582436DOI: 10.1016/j.bbrc.2008.06.050 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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