2Z7X
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide
Summary for 2Z7X
Entry DOI | 10.2210/pdb2z7x/pdb |
Related | 2Z80 2Z81 2Z82 |
Descriptor | Toll-like receptor 2,Variable lymphocyte receptor B, (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, Toll-like receptor 1,Variable lymphocyte receptor B, ... (11 entities in total) |
Functional Keywords | tlr2, tlr1, pam3csk4, lipopeptide, innate immunity, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, cytoplasmic vesicle, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 126181.40 |
Authors | |
Primary citation | Jin, M.S.,Kim, S.E.,Heo, J.Y.,Lee, M.E.,Kim, H.M.,Paik, S.G.,Lee, H.,Lee, J.O. Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide Cell(Cambridge,Mass.), 130:1071-1082, 2007 Cited by PubMed: 17889651DOI: 10.1016/j.cell.2007.09.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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