2Z7K
tRNA-Guanine transglycosylase (TGT) in complex with 2-Amino-lin-Benzoguanine
Summary for 2Z7K
Entry DOI | 10.2210/pdb2z7k/pdb |
Related | 2BBF 2QZR |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, 2,6-diamino-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total) |
Functional Keywords | tim barrel, glycosyltransferase, metal-binding, queuosine biosynthesis, transferase, trna processing |
Biological source | Zymomonas mobilis |
Total number of polymer chains | 1 |
Total formula weight | 43299.40 |
Authors | Ritschel, T.,Heine, A.,Klebe, G. (deposition date: 2007-08-24, release date: 2008-08-26, Last modification date: 2023-11-01) |
Primary citation | Ritschel, T.,Hoertner, S.,Heine, A.,Diederich, F.,Klebe, G. Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT Chembiochem, 10:716-727, 2009 Cited by PubMed: 19199329DOI: 10.1002/cbic.200800782 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.28 Å) |
Structure validation
Download full validation report