2Z64
Crystal structure of mouse TLR4 and mouse MD-2 complex
Summary for 2Z64
Entry DOI | 10.2210/pdb2z64/pdb |
Related | 2Z62 2Z63 2Z65 2Z66 |
Descriptor | Toll-like receptor 4, Lymphocyte antigen 96, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | tlr4, toll-like receptor, md-2, lps, disease mutation, glycoprotein, immune response, inflammatory response, innate immunity, leucine-rich repeat, membrane, transmembrane, secreted, immune system |
Biological source | Mus musculus (house mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein (By similarity): Q9QUK6 Secreted, extracellular space: Q9JHF9 |
Total number of polymer chains | 2 |
Total formula weight | 87782.21 |
Authors | Lee, J.-O.,Kim, H.M.,Park, B.S. (deposition date: 2007-07-22, release date: 2007-09-18, Last modification date: 2023-11-01) |
Primary citation | Kim, H.M.,Park, B.S.,Kim, J.-I.,Kim, S.E.,Lee, J.,Oh, S.C.,Enkhbayar, P.,Matsushima, N.,Lee, H.,Yoo, O.J.,Lee, J.-O. Crystal Structure of the TLR4-MD-2 Complex with Bound Endotoxin Antagonist Eritoran Cell(Cambridge,Mass.), 130:906-917, 2007 Cited by PubMed: 17803912DOI: 10.1016/j.cell.2007.08.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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