2XZC

Crystal Structure of phosphonate-modified recombinant A.17 antibody FAB fragment

Summary for 2XZC

• Entry DOI: 10.2210/pdb2xzc/pdb
• Related: 2XZA
• Descriptor: FAB A.17 HEAVY CHAIN, FAB A.17 LIGHT CHAIN, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: immune system
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 46780.23

Authors

Carletti, E.,Nachon, F.,Nicolet, Y.,Masson, P.,Kurkova, I.,Smirnov, I.,Friboulet, A.,Tramontano, A.,Gabibov, A. (deposition date: 2010-11-24, release date: 2011-09-21, Last modification date: 2020-03-11)

• Primary citation: Smirnov, I.,Carletti, E.,Kurkova, I.,Nachon, F.,Nicolet, Y.,Mitkevich, V.A.,Debat, H.,Avalle, B.,Belogurov, A.A.,Kuznetsov, N.,Reshetnyak, A.,Masson, P.,Tonevitsky, A.G.,Ponomarenko, N.,Makarov, A.A.,Friboulet, A.,Tramontano, A.,Gabibov, A.; Reactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics.; Proc.Natl.Acad.Sci.USA, 108:15954-, 2011; PubMed: 21896761; DOI: 10.1073/PNAS.1108460108

Experimental method

X-RAY DIFFRACTION (1.36 Å)