2XV7

Crystal structure of vascular endothelial growth factor D

Summary for 2XV7

Entry DOI	10.2210/pdb2xv7/pdb
Descriptor	VASCULAR ENDOTHELIAL GROWTH FACTOR D, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (4 entities in total)
Functional Keywords	angiogenesis, lymphangiogenesis, hormone
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	14095.65
Authors	Leppanen, V.-M.,Jeltsch, M.,Anisimov, A.,Tvorogov, D.,Aho, K.,Kalkkinen, N.,Toivanen, P.,Yla-Herttuala, S.,Ballmer-Hofer, K.,Alitalo, K. (deposition date: 2010-10-23, release date: 2011-01-12, Last modification date: 2023-12-20)
Primary citation	Leppanen, V.M.,Jeltsch, M.,Anisimov, A.,Tvorogov, D.,Aho, K.,Kalkkinen, N.,Toivanen, P.,Yla-Herttuala, S.,Ballmer-Hofer, K.,Alitalo, K. Structural Determinants of Vascular Endothelial Growth Factor-D - Receptor Binding and Specificity. Blood, 117:1507-, 2011 Cited by PubMed: 21148085 DOI: 10.1182/BLOOD-2010-08-301549 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation