2XBK
X-ray structure of the substrate-bound cytochrome P450 PimD - a polyene macrolide antibiotic pimaricin epoxidase
Summary for 2XBK
| Entry DOI | 10.2210/pdb2xbk/pdb |
| Related | 2X9P |
| Descriptor | PIMD PROTEIN, PROTOPORPHYRIN IX CONTAINING FE, 4,5-DE-EPOXYPIMARICIN, ... (4 entities in total) |
| Functional Keywords | epoxidation, oxidoreductase |
| Biological source | STREPTOMYCES NATALENSIS |
| Total number of polymer chains | 1 |
| Total formula weight | 45794.98 |
| Authors | Kells, P.M.,Ouellet, H.,Santos-Aberturas, J.,Aparicio, J.F.,Podust, L.M. (deposition date: 2010-04-12, release date: 2010-08-04, Last modification date: 2023-12-20) |
| Primary citation | Kells, P.M.,Ouellet, H.,Santos-Aberturas, J.,Aparicio, J.F.,Podust, L.M. Structure of Cytochrome P450 Pimd Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs Via a Hydroperoxoferric Intermediate. Chem.Biol., 17:841-, 2010 Cited by PubMed: 20797613DOI: 10.1016/J.CHEMBIOL.2010.05.026 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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