2X7R

Crystal structure of a late fusion intermediate of HIV-1 gp41

Summary for 2X7R

Entry DOI	10.2210/pdb2x7r/pdb
Related	1AIK 1DF4 1DF5 1DLB 1G9M 1GC1 1GZL 1K33 1K34 1MZI 1OPN 1OPT 1OPW 1RZJ 2CMR
Descriptor	TRANSMEMBRANE PROTEIN GP41, SODIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	envelope glycoprotein, membrane anchored fusion protein, viral protein
Biological source	HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 LW12.3 ISOLATE More
Cellular location	Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578 P04578
Total number of polymer chains	6
Total formula weight	44094.62
Authors	Natrajan, G.,Buzon, V.,Weissenhorn, W. (deposition date: 2010-03-03, release date: 2010-05-26, Last modification date: 2023-12-20)
Primary citation	Buzon, V.,Natrajan, G.,Schibli, D.,Campelo, F.,Kozlov, M.M.,Weissenhorn, W. Crystal Structure of HIV-1 Gp41 Including Both Fusion Peptide and Membrane Proximal External Regions. Plos Pathog., 6:880-, 2010 Cited by PubMed: 20463810 DOI: 10.1371/JOURNAL.PPAT.1000880 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation