2X6S

Human foamy virus integrase - catalytic core. Magnesium-bound structure.

Summary for 2X6S

Entry DOI	10.2210/pdb2x6s/pdb
Related	2X6N 2X74 2X78
Descriptor	INTEGRASE, MAGNESIUM ION (3 entities in total)
Functional Keywords	viral protein, retroviral integrase, dna-directed dna polymerase, nucleotidyltransferase, dna integration, aspartyl protease, dna recombination, transferase, nuclease, hydrolase
Biological source	HUMAN SPUMARETROVIRUS
Cellular location	Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350
Total number of polymer chains	6
Total formula weight	135612.61
Authors	Rety, S.,Delelis, O.,Rezabkova, L.,Dubanchet, B.,Silhan, J.,Lewit-Bentley, A. (deposition date: 2010-02-19, release date: 2010-08-11, Last modification date: 2023-12-20)
Primary citation	Rety, S.,Rezabkova, L.,Dubanchet, B.,Silhan, J.,Legrand, P.,Lewit-Bentley, A. Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66:881-, 2010 Cited by PubMed: 20693659 DOI: 10.1107/S1744309110022852 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation