2WXY

Crystal structure of mouse angiotensinogen in the reduced form

Summary for 2WXY

Entry DOI	10.2210/pdb2wxy/pdb
Related	2WXW 2WXX 2WXZ 2WY0 2WY1 2X0B
Descriptor	ANGIOTENSINOGEN, SODIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	glycoprotein, hypertension, vasoconstrictor, renin, serpins, vasoactive, angiotensin, hormone
Biological source	MUS MUSCULUS (MOUSE)
Cellular location	Secreted: P11859
Total number of polymer chains	1
Total formula weight	50008.44
Authors	Zhou, A.,Wei, Z.,Carrell, R.W.,Read, R.J. (deposition date: 2009-11-11, release date: 2010-10-20, Last modification date: 2011-07-13)
Primary citation	Zhou, A.,Carrell, R.W.,Murphy, M.P.,Wei, Z.,Yan, Y.,Stanley, P.L.,Stein, P.E.,Pipkin, F.B.,Read, R.J. A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468:108-, 2010 Cited by PubMed: 20927107 DOI: 10.1038/NATURE09505 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation