2WVI

Crystal Structure of the N-terminal Domain of BubR1

Summary for 2WVI

Entry DOI	10.2210/pdb2wvi/pdb
Descriptor	MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 BETA, PRASEODYMIUM ION, ACETATE ION, ... (5 entities in total)
Functional Keywords	tumor suppressor, mitotic checkpoint, tpr, kinase, apoptosis, serine/threonine-protein kinase, cell division, cell cycle, kinetochore, transferase, cytoskeleton
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: O60566
Total number of polymer chains	1
Total formula weight	20062.68
Authors	D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M. (deposition date: 2009-10-16, release date: 2010-03-09, Last modification date: 2011-07-13)
Primary citation	D'Arcy, S.,Davies, O.R.,Blundell, T.L.,Bolanos-Garcia, V.M. Defining the Molecular Basis of Bubr1 Kinetochore Interactions and Anaphase-Promoting Complex/Cyclosome (Apc/C)-Cdc20 Inhibition J.Biol.Chem., 285:14764-, 2010 Cited by PubMed: 20220147 DOI: 10.1074/JBC.M109.082016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation