2WQI
Crystal structure of the human p73 tetramerization domain
Summary for 2WQI
Entry DOI | 10.2210/pdb2wqi/pdb |
Related | 1COK 1DXS 2WQJ 2WTT |
Descriptor | TUMOR PROTEIN P73 (2 entities in total) |
Functional Keywords | p73, p63, p53, tumor suppression, transcription factor, tetramer, oligomerization domain, dna-binding, cooperativity, transcription, cell-cycle control, transcription regulation, apoptosis, cell cycle, development |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 4 |
Total formula weight | 24527.77 |
Authors | Joerger, A.C. (deposition date: 2009-08-21, release date: 2009-10-06, Last modification date: 2024-05-08) |
Primary citation | Joerger, A.C.,Rajagopalan, S.,Natan, E.,Veprintsev, D.B.,Robinson, C.V.,Fersht, A.R. Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation. Proc.Natl.Acad.Sci.USA, 106:17705-, 2009 Cited by PubMed: 19815500DOI: 10.1073/PNAS.0905867106 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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