2WKK

Identification of the glycan target of the nematotoxic fungal galectin CGL2 in Caenorhabditis elegans

Summary for 2WKK

• Entry DOI: 10.2210/pdb2wkk/pdb
• Related: 1UL9 1ULC 1ULD 1ULE 1ULF 1ULG
• Descriptor: GALECTIN-2, beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose, beta-D-galactopyranose-(1-4)-alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: sugar-binding protein, lectin, galectin, secreted, cell wall, sugar binding, sugar binding protein, beta-galactoside binding lectin, fruiting body, extracellular matrix
• Biological source: COPRINOPSIS CINEREA
• Cellular location: Secreted, extracellular space, extracellular matrix : Q9P4R8
• Total number of polymer chains: 4
• Total formula weight: 68895.77

Authors

Butschi, A.,Titz, A.,Waelti, M.,Olieric, V.,Paschinger, K.,Xiaoqiang, G.,Seeberger, P.H.,Wilson, I.B.H.,Aebi, M.,Hengartner, M.O.,Kuenzler, M. (deposition date: 2009-06-14, release date: 2010-01-19, Last modification date: 2023-12-13)

• Primary citation: Butschi, A.,Titz, A.,Walti, M.A.,Olieric, V.,Paschinger, K.,Nobauer, K.,Guo, X.,Seeberger, P.H.,Wilson, I.B.H.,Aebi, M.,Hengartner, M.O.,Kunzler, M.; Caenorhabditis Elegans N-Glycan Core Beta-Galactoside Confers Sensitivity Towards Nematotoxic Fungal Galectin Cgl2.; Plos Pathog., 6:E717-, 2010; PubMed: 20062796; DOI: 10.1371/JOURNAL.PPAT.1000717

Experimental method

X-RAY DIFFRACTION (1.5 Å)