2WBU

CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA

Summary for 2WBU

• Entry DOI: 10.2210/pdb2wbu/pdb
• Related: 2WBS
• Descriptor: KRUEPPEL-LIKE FACTOR 4, 5'-D(*DGP*DAP*DGP*DGP*DCP*DGP*DTP* DGP*DGP*DC)-3', 5'-D(*DGP*DCP*DCP*DAP*DCP*DGP*DCP* DCP*DTP*DC)-3', ... (5 entities in total)
• Functional Keywords: transcription-dna complex, nucleus, activator, dna-binding, zinc-finger, transcription, metal-binding, transcription regulation, transcription/dna
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Nucleus: Q60793
• Total number of polymer chains: 3
• Total formula weight: 16861.15

Authors

Schuetz, A.,Zocher, G.,Carstanjen, D.,Heinemann, U. (deposition date: 2009-03-05, release date: 2010-04-07, Last modification date: 2023-12-13)

• Primary citation: Schuetz, A.,Nana, D.,Rose, C.,Zocher, G.,Milanovic, M.,Koenigsmann, J.,Blasig, R.,Heinemann, U.,Carstanjen, D.; The Structure of the Klf4 DNA-Binding Domain Links to Self-Renewal and Macrophage Differentiation.; Cell.Mol.Life Sci., 68:3121-, 2011; PubMed: 21290164; DOI: 10.1007/S00018-010-0618-X

Experimental method

X-RAY DIFFRACTION (2.5 Å)