2WBG

Structure of family 1 beta-glucosidase from Thermotoga maritima in complex with 3-imino-2-oxa-(+)-castanospermine

Summary for 2WBG

Entry DOI	10.2210/pdb2wbg/pdb
Related	1OD0 1OIF 1OIM 1OIN 1UZ1 1W3J 2CBU 2CBV 2CES 2CET 2J75 2J77 2J78 2J79 2J7B 2J7C 2J7D 2J7E 2J7F 2J7G 2J7H 2JAL 2VRJ 2WC3 2WC4
Descriptor	BETA-GLUCOSIDASE A, (3Z,5S,6R,7S,8R,8aR)-3-(octylimino)hexahydro[1,3]oxazolo[3,4-a]pyridine-5,6,7,8-tetrol, ACETATE ION, ... (4 entities in total)
Functional Keywords	castanospermine, glycoside hydrolase, polysaccharide degradation, cellulose degradation, carbohydrate metabolism, family 1, hydrolase, inhibitors, glycosidase
Biological source	THERMOTOGA MARITIMA
Total number of polymer chains	4
Total formula weight	217087.21
Authors	Aguilar, M.,Gloster, T.M.,Turkenburg, J.P.,Garcia-Moreno, M.I.,Ortiz Mellet, C.,Davies, G.J.,Garcia Fernandez, J.M. (deposition date: 2009-02-27, release date: 2009-04-14, Last modification date: 2023-12-13)
Primary citation	Aguilar-Moncayo, M.,Gloster, T.M.,Turkenburg, J.P.,Garcia-Moreno, M.I.,Ortiz Mellet, C.,Davies, G.J.,Garcia Fernandez, J.M. Glycosidase Inhibition by Ring-Modified Castanospermine Analogues: Tackling Enzyme Selectivity by Inhibitor Tailoring. Org.Biomol.Chem., 7:2738-, 2009 Cited by PubMed: 19532990 DOI: 10.1039/B906968B PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation