2W5B

Human Nek2 kinase ATPgammaS-bound

Summary for 2W5B

Entry DOI	10.2210/pdb2w5b/pdb
Related	2JAV 2W5A 2W5H
Descriptor	SERINE/THREONINE-PROTEIN KINASE NEK2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	transferase, meiosis, mitosis, cytoplasm, metal-binding, phosphoprotein, nucleotide-binding, magnesium, cell cycle, atp-binding, centrosome splitting, cell division
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Nucleus. Isoform 1: Nucleus, nucleolus. Isoform 2: Cytoplasm: P51955
Total number of polymer chains	1
Total formula weight	33215.46
Authors	Bayliss, R. (deposition date: 2008-12-08, release date: 2008-12-23, Last modification date: 2013-01-30)
Primary citation	Westwood, I.,Cheary, D.M.,Baxter, J.E.,Richards, M.W.,Van Montfort, R.L.,Fry, A.M.,Bayliss, R. Insights Into the Conformational Variability and Regulation of Human Nek2 Kinase. J.Mol.Biol., 386:476-, 2009 Cited by PubMed: 19124027 DOI: 10.1016/J.JMB.2008.12.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation