2W51
Human mesencephalic astrocyte-derived neurotrophic factor (MANF)
Summary for 2W51
Entry DOI | 10.2210/pdb2w51/pdb |
Related | 2W50 |
Descriptor | PROTEIN ARMET (1 entity in total) |
Functional Keywords | manf, cdnf, saposin, secreted, er stress, phosphoprotein, neurotrophic factor, sialic acid, glycoprotein, growth factor, hormone |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 18195.14 |
Authors | Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A. (deposition date: 2008-12-03, release date: 2009-03-17, Last modification date: 2024-05-01) |
Primary citation | Parkash, V.,Lindholm, P.,Peranen, J.,Kalkkinen, N.,Oksanen, E.,Saarma, M.,Leppanen, V.M.,Goldman, A. The Structure of the Conserved Neurotrophic Factors Manf and Cdnf Explains Why They are Bifunctional. Protein Eng.Des.Sel., 22:233-241, 2009 Cited by PubMed: 19258449DOI: 10.1093/PROTEIN/GZN080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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